Increased PaCO2 in the blood indicated inadequate alveolar ventilation or hypercarbia. Hypercarbia is more severe, but is harder to detect. The following are signs of hypercarbia:
Specific causes of upper airway obstruction include croup and anaphylaxis.
Croup is a condition where the upper airway is affected due to an acute viral infection. Symptoms include barking cough, stridor and hoarseness. Treatment of croup can vary due to the severity of the disease. Management of croup includes the following:
Anaphylaxis is a type I hypersensitivity allergic reaction that can causes intense bronchoconstriction in which the patient may stop breathing. The following table shows the actions needed for the treatment of anaphylaxis.
Specific causes of lower airway obstruction include asthma and bronchiolitis.
Bronchiolitis
Bronchiolitis is inflammation of the bronchioles with coughing, shortness of breath and wheezing. Management of bronchiolitis includes the following:
- Nasal or oral suctioning
- Ancillary testing – chest x-ray, arterial blood gas analysis and viral studies
Asthma
Asthma is a chronic inflammatory disease of the airway with symptoms of coughing, shortness of breath, wheezing and tightness of the chest. The following table illustrates the management of asthma.
Lung Tissue Disease |
Anatomy | Clinical conditions with the lungs |
Causes | - Pneumonia
- Pulmonary edema
- ARDS
- Trauma
- Allergic reaction
- Toxins
- Vasculitis
|
Signs and Symptoms | - Tachypnea
- Tachycardia
- Crackles
- Increased respiratory effort
- Grunting
- Hypoxemia
- Decreased breath sounds
|
Management | Management of all tissue lung disease includes: - Use positive expiratory pressure for hypoxemia
- Administer humidified high-flow nasal cannula
- Monitor tissue perfusion and cardiac output
|
Specific causes of lung tissue disease include pneumonia, chemical pneumonitis, aspiration pneumonitis, cardiogenic pulmonary edema and noncardiogenic pulmonary edema (ARDS).
Pneumonia
Pneumonia is inflammation of the alveoli of the lungs due to infection by bacteria, viruses, fungi and parasites. Pneumonia presents with fever, chest pain, cough, difficulty in breathing. The management of pneumonia includes:
- Antimicrobial therapy
- Albuterol by MDI or nebulizer
- Use CPAP or BiPAP
- Normalize temperature by treating fever
- Conduct ancillary testing
Chemical Pneumonitis
Chemical pneumonitis is inflammation of the lungs caused by breathing in toxic substances. Toxic substances include dust, fumes, irritant gases, hydrocarbons. Management of chemical pneumonitis is done by:
- Use of CPAP or BiPAP
- Give nebulized bronchodilator
- Consultation of a severity center
Aspiration Pneumonitis
Aspiration pneumonitis is inflammation of the lungs caused by content of the stomach such as stomach acid and enzymes. For treatment of aspiration pneumonitis consider the following options:
- Use of CPAP or BiPAP
- Administer antibiotics for fever and infiltrates
Cardiogenic Pulmonary Edema
Cardiogenic pulmonary edema occurs when there is an accumulation of fluid in the lung interstituim and alveoli because of elevated pulmonary capillary pressure. Most common cause of cardiogenic pulmonary edema is congestive heart failure and acute myocardial dysfunction. Management of cardiogenic pulmonary edema includes:
- Ventilatory support
- Medical therapy by reducing left atrial pressure, left ventricular afterload and give inotropic or inodilator therapy
- Decrease temperature and breathing by reducing metabolic demand
Noncardiogenic Pulmonary Edema (ARDS)
Acute respiratory distress syndrome is inflammation of the lung parenchyma causing difficulty in breathing, hypoxemia and multiple organ failure. ARDS as defined by the American Heart Association is, acute onset, PaO2/FiO2 <300, bilateral infiltrates on chest x-ray, and no evidence for a cardiogenic cause of pulmonary edema. Management of ARDS includes:
- Monitor the patient’s pulse oximetry, end tidal CO2, cardiac markers
- Get labs like ABG, venous blood gas and CBC
- Give continuous ventilation
Disordered Control of Breathing |
Anatomy | Problems associated with the respiratory system |
Causes | - Seizures
- CNS infections
- Head injury
- Brain tumor
- Hydrocephalus
- Neuromascular disease
|
Signs and Symptoms | - Irregular respiratory rate
- Variable respiratory effort
- Shallow breathing – causes hypoxemia and hypercarbia
- Central apnea
|
Management | Management of disordered control of breathing includes: - Conduct the ABC assessment
|
Specific causes of disordered control of breathing include increased intracranial pressure (ICP), poisoning or drug overdose, and neuromuscular diseases.
Increased Intracranial Pressure
Increased intracranial pressure can be caused by:
- Meningitis
- Encephalitis
- Intracranial abscess
- Subarachnoid hemorrhage
- Subdural or epidural hematoma
- Traumatic brain injury
- Hydrocephalus
- Central nervous system tumor
Proper management of respiratory distress or failure due to increased ICP includes:
- Jaw thrust maneuver
- Open airway
- Give 20 mL/kg IV isotonic crystalloid
- Give hypertonic saline, osmotic agent
- Avoid hypothermia and hypotension
- Treat agitation
Poisoning and Drug Overdose
Poisoning and drug overdose is one of the most common and frequent causes of respiratory distress in infants and children. The following actions must be taken to treat this type of respiratory distress.
- Contact the poison control center
- Administer the antidote to the poison
- Suction airway if patient vomits
- Conduct the ancillary test
Neuromuscular Disease
Neuromuscular disease is broad term that is given to various diseases that impair muscle control and causes spasticity or paralysis. Children with neuromuscular diseases which affect respiration have the following symptoms:
- Cough
- Atelectasis
- Restrictive lung disease
- Pneumonia
- Chronic respiration insufficiency
- Respiratory failure
For management of neuromuscular disease in children complete the ABC assessment, which includes supporting the airway, breathing and circulation.